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Title :画像濃度を用いた細胞凝集塊形態特性の評価の検討
Authors :渡部 俊樹
下戸 健
Issue Date :5-Apr-2020
Abstract :Our research group has established a technique to make three-dimensional cell constructs using only cells. The cell constructs are made using spheroids consisting of only cells. The quality of the spheroids is important as it is necessary to provide reproducible spheroids. Therefore, it is necessary to morphologically evaluate spheroids non-invasively. The quality of spheroids was evaluated regarding area, diameter, and circularity. However, the concentration distribution of the spheroids had not previously been visualized. This study aimed to visualize the cell distribution inside spheroids using pseudo-color display processing. By applying pseudo-color processing to the grayscale spheroid images, we succeeded in visually grasping cell distribution and shape. In the future, we will actually observe inside the spheroid and aim to further improve the accuracy by correlating with the specific conditions.
Type Local :紀要論文
ISSN :24345725
Publisher :福岡工業大学総合研究機構
Comment :情報科学研究所(Computer Science Laboratory)
URI :http://hdl.handle.net/11478/1489
citation :福岡工業大学総合研究機構研究所所報
Citation :福岡工業大学総合研究機構研究所所報 Vol.2 p.95 -98
Appears in Collections:Vol.2

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